Not only is it safe, but the combination of Retinol and Alpha Beta® Daily peels will leave your skin glowing! Both our peels and retinol products are designed to be used together. If you have sensitive skin and/or are worried about irritation, you can use the peel in the morning and the retinol at night. If you are new to retinol, you can start by introducing retinol to your routine once or twice a week and gradually work your way up to everyday use.